Retinoic Acid Receptor, alpha (RARA) Peptide
RARA
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936051
Quick Overview for Retinoic Acid Receptor, alpha (RARA) Peptide (ABIN936051)
Target
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YESVEVGGPT PNPFLVVDFY NQNRACLLPE KGLPAPGPYS TPLRTPLWNG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RARA antibody,
Alternative Names: RARA control peptide, RARA antibody Blocking Peptide, Anti-RARA Blocking Peptide, Retinoic Acid Receptor Alpha Blocking Peptide, NR1B1 Blocking Peptide, RAR Blocking Peptide
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Retinoic Acid Receptor, alpha (RARA) peptide
RARA Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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Background
- Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
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Molecular Weight
- 51 kDa
Target
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